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1. What is the C. Douglas McFadyen Memorial Fund?

The C. Douglas McFadyen Memorial Fund was established in 2000 to assist in underwriting an immunological approach to cancer treatment, also known as Biological Therapy. The first recipient of funds was Dr. Michael Morse at Duke University's Department of Medicine to assist his research team in publishing a paper entitled 'Surrogate markers of response to cancer immunotherapy.' It was published by Ashley Publications in 2001, Vol 2: 153-158.

This article puts forth the case for 'developing intermediate markers to help prioritize which agents to test in prospective randomized Phase III trials.' Evidently there is growing enthusiasm to this approach which seeks to actively stimulate antitumor immune responses.

2. Why is Biological Therapy the focus of the Fund?

Of the various treatments that C. Douglas McFadyen researched and received in response to his own diagnosis of cancer, the one that he felt was most promising is an immunological approach. Although too far along in his own disease process for this approach to be a cure, he still believed that this form of cancer therapy should be encouraged and was, by far, less traumatic for the patient to undergo than many of the chemotherapy and radiation treatments presently offered.

3. What is an immunological approach to cancer treatment?

As medical researchers have turned their attention to studying the immune system, there has been a growing interest in stimulating this defense system of the body for purposes of both prevention and cure for cancer in its variety of forms. This has been combined with cutting edge research in cell biology so that a form of inoculation can be given to patients that specifically targets their form of cancer yet is also compatible with their own biology. In simple terms, the body's ability to fight off the cancer and any resulting tumors is aided by having antitumor agents injected in the blood system which were specifically designed for that type of cancer.

3. Where can I find out more about this approach to cancer treatment?

The Duke University Department of Clinical Research in Oncology is seeking to bring novel therapies to clinical trial. Their website is rich with information. - click here to review it now.

For more information about research being conducted by Dr. Michael Morse - click here to go there now.

To contact Dr. Michael A. Morse please see the website page for Duke University faculty by clicking here.

4. How can I get involved in supporting this research?

If you wish to make a direct contribution to the C. Douglas McFadyen Memorial Fund, please contact Barbara McFadyen at the information shown below.

Eight Gates Music raises money to support this research in several ways: CD sales, classical Indian music concerts, and workshops on Nada Yoga. More information about our CDs can be found on the 'Catalog' page on this website. More information about concerts and workshops can be found on the 'Events' page.

K. Sridhar and Doug McFadyen - 1997 India K. Sridhar and Doug McFadyen - 1997 India